The Great Plains became an important component of television programming soon after the medium became successful on a national level. Programs included documentaries as well as traditional entertainment.

Noncommercial educational (later called public) broadcasting led the way with a series entitled . The thirty-nine half-hour programs were produced in the 1950s by Jack McBride of KUON-TV at the University of Nebraska. The first thirteen programs dealt with the paleontology of the region. The second set of thirteen programs considered archaeology. The third group emphasized Great Plains history. The Ford Foundation provided the funding, and the series was broadcast on educational/public television stations.

In commercial broadcasting many popular programs about life on the American frontier did not indicate specific locations. Others that might be related to the Great Plains such as were actually filmed in other areas. , the highest-rated commercial network program of the early 1980s, included episodes about the Texas Plains even though the city is peripheral to the region.

One of the best known of the series clearly identified with the Great Plains was Gunsmoke (CBS, 1955-75), which starred James Arness as U.S. marshal Matt Dillon. , which continued to enjoy success as a syndicated off- network rerun, was set in Dodge City, Kansas, in the 1870s and 1880s. The show's twenty years on the network included thirty-minute as well as sixty-minute versions. Amanda Blake (Kitty), Milburn Stone (Doc), Dennis Weaver (Chester), and Burt Reynolds (Quint) were key characters in this depiction of life in a western Kansas cattle town.

Several other westerns were specifically set in the Plains. (ABC, 1963) included Larry Ward, Chad Everett, and Jack Elam as U.S. marshals. (ABC, 1974) featured a cattle drive from a New Mexico ranch to Dodge City, Kansas, with a trail crew consisting of eleven nine- to fifteen-year-old children. (syndicated, 1951), based on the O. Henry character and probably the first television series to be filmed in color, involved a Robin Hood hero (played by Duncan Renaldo) and his partner, Pancho (Leo Carillo), in New Mexico during the 1890s. (NBC, 1958 and 1965) cast Sallie Brophie as a widow hotel owner in 1880s Montana. Tommy Nolan played her son Jody who, seated on corral fence, plays his harmonica and narrates each story. (NBC, 1965) placed Chuck Conners in southeastern Wyoming in the 1870s as a former soldier trying to clear his name. (ABC, 1971–73) followed two bank robbers who, after ending criminal careers, are promised pardons if they prove themselves worthy for twelve months in Kansas during the 1890s. A comedy Western, (ABC, 1965–67), featured Forrest Tucker, Larry Storch, and Ken Berry in the Union army in 1866 in Kansas.

Some programs were not located in identifiable states or towns but depicted the region more generally. One example, (ABC, 1977), a three-part miniseries about a Virginia family homesteading in the Great Plains, brought former star James Arness back to the region with costars Eva Marie Saint and Bruce Boxleitner. Another example, (NBC, ABC, 1957. 65), followed a wagon master (Ward Bond until his death in 1960, when he was replaced by John McIntire) who led pioneers from a starting point at St. Joseph, Missouri, across the Plains to final destinations in the Far West. The eight-hour miniseries (CBS, 1989) offered solid performances by Robert Duvall, Tommy Lee Jones, and Anjelica Huston during a cattle drive from Lonesome Dove, Texas, to Montana. (CBS, 1993) continued the story with Barbara Hershey and William Peterson as the stars.

A different type of series, (CBS, 1960-64), followed the adventures of two young men, played by Martin Milner and George Maharis, as they drove a white Chevrolet Corvette through the Great Plains and points west on that famous highway. The series benefited from successful recordings of the theme song, which was written by Nelson Riddle.

Television programming tends to follow audience trends. Much of the emphasis in the Great Plains followed the interest in Westerns during the early years of the medium. When the Western declined in popularity, the Great Plains tended to fade from the screen. But as specialized locations returned to popularity, programming such as the miniseries and documentaries on the Oregon Trail, Lewis and Clark, and Native Americans have brought the focus back to the region.

See also IMAGES AND ICONS: Dodge City, Kansas / LITERARY TRADITIONS: The Western / TRANSPORTATION: Route 66.